In the United States, nearly half of all adults have hypertension (or an elevated blood pressure). In addition, people with HIV over 50 years of age are 50 percent more likely to have hypertension than people of a similar age without HIV. Although the ADAP formulary includes multiple medications for the treatment of hypertension, few of these medications have been combination pills. Initial treatment for many patients with hypertension includes low to moderate doses of two medications with complementary mechanisms of action. Single-pill combination therapy can lower blood pressure more effectively than monotherapy and the lower doses of each medication results in fewer dose-related side effects. To provide options for combination hypertension therapy and to ensure that ADAP clients receive care consistent with current national guidelines, the following single-pill combination medications have been added to the ADAP formulary: