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Sexually Transmitted diseases Control Branch

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​​Syphilis

SyphilisSyphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. Untreated infection can lead to long-term health problems, including brain disease. Syphilis increases both transmission and acquisition of HIV. Tests and treatment are available.

Information on congenital syphilis.​​​​​

Resources for Providers

**Please note, the STI treatment guidelines and syphilis screening recommendations referenced in this document are out of date. Please refer to the 2021 STI Treatment guidelines for the current treatment regimens, and California Department of Public Health (CDPH) Updates Syphilis Screening Recommendations.​

Note: Please check our archive webpage for additional Dear Colleague Letters, Health Alerts and Recommendations, and All Facility Letters.​​


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