Genetic disease screening program

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Screening Information System (SIS) 1.0

Important Update:

Note: Before you can obtain access to the Screening Information System (SIS) you must read, sign and submit an Oath of Confidentiality (PDF). For NBS, email the form to NBS.OST@cdph.ca.gov. For PNS, contact your program lead for information on where to send it.

Attention Newborn Screening (NBS) Screening Information System (SIS) User!

We’re pleased to announce that the NBS program will migrate from SIS 1.0 to SIS 2.0 on May 18, 2026!

What’s Changing and Why?

SIS 2.0 is powered by Microsoft Dynamics, featuring a streamlined interface for operational efficiency.
SIS 2.0 has better compatibility with case management systems already in use, leading to more reliable access and steady performance.

When Will Training Be Available?

Starting in March 2026, we will begin offering training tailored to active NBS SIS 1.0 users according to their current roles. This training is designed to familiarize you with the upgraded NBS SIS 2.0 platform.

Why This Matters:

Participating in training is essential to ensure a smooth transition and prepare users to perform their job responsibilities using SIS 2.0.

How will training be conducted?

We will offer a variety of training resources to support all users. Users will have access to webinars, virtual classroom training, user guides, and recorded videos.

Next Steps:

Keep an eye out for upcoming meeting invitations and additional resources to help you prepare.

NBS SIS 2.0 Migration Timeline (November 2025 – June 2026)

The timeline is divided into three horizontal sections: Milestones, Communications, and Training. Each section contains scheduled events aligned with the months of November 2025 through June 2026. Different icons and colors indicate the type of event (Milestone, Communication, Meeting, Training).

Milestones

System Testing is ongoing from November 2025 through May 2026.
Go-Live is scheduled for May 2026.

Communications

December 2025: "NBS SIS 2.0 Announcement" and "Survey"
February 2026: "Training Announcement"
March 2026: "Project Update" and "Live NBS SIS 2.0 Community Update"
April 2026: "Live NBS SIS 2.0 User Update" and "Prepare for Go-Live & Training Reminder" and "Survey"
May 2026: "Go-Live Announcement"
June 2026: "Post Go-Live Support Update"