More than 2.8 million illnesses and 35,000 deaths are attributed to infections with antimicrobial-resistant organisms in the United States each year. Among Californians, this translates to roughly 360,000 illnesses and nearly 4,500 deaths.
The Centers for Disease Control and Prevention (CDC)
Antibiotic Resistance (AR) Threats in the United States, 2019 Report (PDF) includes
carbapenem-resistant Enterobacterales (CRE) and
Candida auris (C. auris),
Clostridioides difficile (C. difficile), Carbapenem-resistant Acinetobacter and multidrug-resistant
Pseudomonas aeruginosa as
urgent and serious threats.
The U.S. Department of Health and Human Services
National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB), 2020-2025 (PDF) outlines a coordinated plan to respond to these AR threats.
Core actions to prevent resistance include improving antimicrobial prescribing through stewardship, reducing infections, and preventing transmission of antimicrobial-resistant bacteria.
Antimicrobial Stewardship Information
Antimicrobial Stewardship Honor Roll
CDPH connects clinicians, infection preventionists, laboratorians, and public health practitioners to testing resources for the rapid detection of antimicrobial-resistant pathogens.
California Antimicrobial Resistance Lab-Epi Alliance
CDPH utilizes a systematic framework for containing spread of antimicrobial-resistant pathogens.
Candida auris (C. auris)
Carbapenem-resistant Acinetobacter (CRAB)
Carbapenem-resistant Enterobacterales (CRE)
Carbapenem-resistant Pseudomonas aeruginosa (CRPA)
Clostridioides difficile Quicksheet (PDF)