Genetic Disease Screening Program

Hemoglobin Trait Carrier Rate by Race/Ethnicity in California Newborns (2013–2022)

Race/Ethnicity	Hb S Trait	Hb C Trait	Hb D Trait
African-American/Black	1 in 17	1 in 59	1 in 2,713
Native American	1 in 103	1 in 367	1 in 2,531
Latinx/Hispanic	1 in 192	1 in 1,492	1 in 2,074
Middle Eastern	1 in 291	1 in 3,153	1 in 488
Pacific Islander (includes Guamanian, Hawaiian, Samoan)	1 in 297	1 in 1,144	1 in 4,003
White	1 in 624	1 in 2,909	1 in 2,637
Asian Indian	1 in 684	1 in 30,968	1 in 224
Filipino	1 in 944	1 in 4,266	1 in 2,812
Southeast Asian (includes Vietnamese and other Southeast Asian)	1 in 1,473	1 in 10,312	1 in 2,101
East Asian (includes Chinese, Japanese, and Korean)	1 in 4,819	1 in 17,007	1 in 8,504

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