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Genetic disease screening program

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​Screening Information System (SIS) 2.0

Important Update:

We’re pleased to announce that all GDSP programs are now on SIS 2.0: Prenatal Screening (PNS), Biobank, and Newborn Screening (NBS). Effective May 18, 2026, NBS users have joined SIS 2.0.​

SIS 2.0 M​aterials

Note: The Oath of Confidentiality will now be captured electronically for each user upon first-ti​me login to SIS 2.0.

See the Genetic Diseas​​e Screening Program Privacy Policy for further information on confidentiality.

To access pertinent Californ​ia Codes, go to the Official California Legislative Information​ website.

Newborn Screening (​NBS) Program Users​

Attention Newborn Screening (NBS) Screening Information System (SIS) User!

We’re pleased to announce that the NBS Program has migrated from SIS 1.0 to SIS 2.0 as of May 18, 2026!

NBS SIS 2.0 Training Mate​rials

Please reach out to your designated Persona Lead for access to available training materials and reach out to NBSSIS2.0@cdph.ca.gov​ for support.​

Prenatal Screening (PNS) Program Users​

Favorited pages either bookmarked or saved as SIS 1.0 should be updated to the new SIS 2.0 locations after the Revised Program's launch on September 19, 2022.

Access to the SIS 2.0 BI Reports will be available after the launch of the Revised Program.​​​

For help with SIS 2.0, please contact PNS@cdph.ca.gov. ​

Live Demos

The web-based training videos are provided in HTML format which is unable to incorporate keyboard-only navigation. If required, please submit a request to PNS@cdph.ca.gov and an MP4 file can be provided.

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SIS 2.0 Web-based Training Videos

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