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Division of Communicable Disease Control


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Mpox Vaccine Eligibility Has Expanded!

Get your safe and effective mpox vaccine at a pro​vider near you.

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Check with your local health department (LHD) for more information on case reporting and treatment options available.

Health Advisories and Updates

Health Care Providers

Topics: Clinical Recognition and Considerations | Mpox Treatment​ |​ Provider Reporting | Infection Prevention and Waste Management in Healthcare Settings

Clinical Recognitions and Considerations

Mpox Treatment

Infection Prevention and Waste Management in Healthcare Setting


As a reminder, mpox testing is available at many commercial laboratories and providers should consult their laboratory for submission criteria. Providers may otherwise contact their local health department to inquire about testing through the public health lab if needed.

Local Health Departments​

Topics: Case Reporting | Case Investigation and Other Setting-Specific Guidance​ |​ Vaccine Distribution and Administration​ | Messaging and Communications Toolkit​

Case Reporting

  • Case Definitions for Use in the 2022 Mpox Response​ – CDC guidance for case definitions and criteria, including for reinfections.
    • Interim reinfection reporting to CDPH:
      • Create new incident ID for suspected reinfection cases and attach ELR.
      • ​Assess for case criteria per CDC definition (i.e., symptom resolution between episodes) and note “reinfection” within notes tab along with primary infection incident ID.
      • ​If possible, forward any specimens that may meet reinfection criteria to VRDL for WGS.
      • Send secure email to
  • Death reporting – See CDC MMWR on mpox-associated deaths. For public health surveillance in CalRedie, use death certificate (i.e., if mpox is listed on the death certificate as a primary or significant contributing factor).
  • See CalRedie document repository or LHJ SharePoint for further reporting information—email​ to request SharePoint access.

Case Investigation and Other Setting-Specific Guidance

Vaccine Distribution and Administration​

Messaging and Communications Toolkits

Community Guidance

Topics: How to Prevent Mpox | If You Have Mpox​ |​ Prevention in Non-Clinical Settings

How to Prevent Mpox

If You Have Mpox

Prevention in Non-Clinical Settings




Archived Guidance306Archived Guidance<ul><li>​​​​​<a href="/Programs/CID/DCDC/Pages/Mpox/Intradermal-administration-of-JYNNEOS-smallpox-and-mpox-vaccine-recommended-to-extend-scarce-supplies-11-3-22.aspx">Interim guidance: Intradermal administration of JYNNEOS smallpox and mpox vac​cine recommended to extend scarce supplies</a> | <a href="/Programs/CID/DCDC/CDPH%20Document%20Library/Mpox/Interim-guidance-Intradermal-administration-of-JYNNEOS-smallpox-and-Mpox--es.pdf" style="text-decoration-line:underline;">Spanish</a><span> (PDF) </span></li><li> <a href="/Programs/CID/DCDC/Pages/Mpox-vs-COVID19.aspx" target="_blank">Mpox vs. COVID-19​</a></li><li>​​​<a href="/Programs/CID/DCDC/Pages/Mpox/Mpox-Exposure-Management.aspx" target="_blank">Mpox Exposure Management​</a> – CDPH guidance regarding recommendations for management of persons with possible exposure to someone with mpox in community settings.​​<br></li><li> <a href="/Programs/CID/DCDC/CDPH%20Document%20Library/Mpox/Severe-Mpox-Infection-in-People-with-Untreated-HIV-Weakened-Immune-System-Letter.pdf" target="_blank">​​Severe Mpox Infection in People with Untreated HIV and a Weakened Immune System​</a> (PDF) - CDPH health notice regarding mpox <br> </li><li> <span style="font-size:13px;"> <a href="/Programs/CID/DCDC/Pages/Mpox/Mpox-Home-Isolation-Guidance-for-the-General-Public.aspx" target="_blank">Mpox Home Isolation Guidance for the General Public</a> | <a href="/Programs/CID/DCDC/CDPH%20Document%20Library/Mpox/Mpox-Home-Isolation-Guidance--es.pdf" target="_blank">Spanish​</a> (PDF)​</span><br></li><li><span style="font-size:13px;">2022 CDPH Health Advisories</span></li><ul><li><span style="font-size:13px;"><a href="/Programs/OPA/Pages/CAHAN/Healthcare-Provider-Advisory-Guidance-for-Safe-Specimen-Collection-From-MPX-Lesions.aspx">October 5, 2022​</a></span></li><li><span style="font-size:13px;"><a href="/Programs/OPA/Pages/CAHAN/CAHAN-MPX-pediatric-testing-09-09-22.aspx">September 9, 2022</a></span></li><li><span style="font-size:13px;"><a href="/Programs/OPA/Pages/CAHAN/Title17-Revisions-Section2500-CA-Code-Regulations.aspx">September 6, 2022</a></span></li><li><span style="font-size:13px;"><a href="/Programs/OPA/Pages/CAHAN/CAHAN-MPX-commercial-lab-testing-08-30-2022.aspx">August 30, 2022</a></span></li><li><span style="font-size:13px;"><a href="/Programs/CID/DCDC/Pages/Health-Advisory-Monkeypox-Virus-5-27-22.aspx">May 27, 2022</a></span></li><li><span style="font-size:13px;"><a href="/Programs/CID/DCDC/Pages/Health-Advisory-Monkeypox-Virus.aspx">May 20, 2022</a></span></li></ul></ul><p></p>

How Can We Help You?

Connect with CDPH for additional mpox resources.

Contact CDPH STD Control Branch Mpox Team

If you need further clarification or have questions, comments, and concerns regarding CDPH Mpox, submit an inquiry​.

Contact Your Local Public Health Department

Reach out to your local health department with any questions.​

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