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Division of Communicable Disease Control

Mpox

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Related Materials

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Get Your Mpox Vaccine Today!

For the most protection, make sure you get both doses.

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Related Materials

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Provider Resources:

  • CDPH Mpox Guidance for Providers

What you need to know

  • Mpox is an infection caused by the monkeypox virus. It usually causes a mild illness with a contagious rash that lasts several weeks.

  • Mpox can spread person-to-person through close physical contact with someone who has mpox.

  • Protect yourself by getting both doses of the mpox vaccine if you or your sex partner(s) may be at risk for mpox.​

  • Talk with your health care provider if you have mpox symptoms. They may recommend medicines to help your symptoms.​

Current situation​

​Mpox in California

The current risk of mpox (formerly known as monkeypox) to the general public remains low. 

  • ​​Clade I mpox: Since 2024, there have been occasional travel-related cases outside of central Africa—including in California.  ​

    • As of October 2025, community spread of clade I mpox is happening in California. Enhanced public health monitoring is ongoing. Risk to the general public remains low​.

  • ​Clade II mpox: Mpox has been spreading at low levels within California since 2022.  ​

  • The mpox vaccine is recommended for those who may be at risk for mpox exposure​. This includes before traveling to areas where clade I mpox is spreading​. 

CDPH response 

  • ​Since 2022, CDPH has worked closely with local health departments and community organizations. This has improved access to mpox vaccines, testing, and treatment for those at highest risk. 

  • CDPH continues to work with local, state, and federal partners to monitor mpox and prevent outbreaks. 

  • CDPH is working to help health care providers and the public become familiar with the symptoms and appearance of mpox. 

Mpox basics 

What is mpox and how do you get it? 

Mpox is an infection caused by the monkeypox virus. There are two types of mpox, clade I and clade II. Both types cause similar symptoms and can be prevented using the same methods. 

Mpox mainly spreads through sex or close contact to a person who has mpox infection: 

  • Sex (oral, anal, or vaginal)

  • ​​Intimate physical contact such as  cuddling or massages

  • Direct skin-to-skin contact with the rash, scabs, or body fluids that touched sores 

  • Sharing a living space or personal items with someone who has mpox 

  • Spread from a pregnant person with mpox to the fetus or baby 

Casual contact, like one might have in an airplane, office, or store, is unlikely to spread mpox. 

What are the symptoms of mpox? 

After being exposed to mpox, it can take up to 21 days for symptoms to show. Mpox can start with symptoms such as: 

  • Fever 

  • Sore throat 

  • Low energy 

  • Swollen lymph nodes 

  • Body aches 

Within about 3 days, a rash or sore(s) develops. 

  • ​It can look like a pimple or blisters​ and may feel painful or itchy. 

  • The rash or sore(s) may be located anywhere on the body. This includes the genitals (penis, testicles, labia, and vagina) or anus (butt). 

  • The sores go through several stages, including scabs, before healing. It may leave scarring. 

See a health care provider if you have these symptoms. ​

How do I avoid getting mpox? 

  • ​Get vaccinated to protect yourself if you think you or your sex partners may be at risk for mpox. For the most protection, make sure you get both vaccine doses. 

  • Talk to your sexual partner(s). Ask about recent illnesses, rashes, or recent international travel. 

    • ​Mpox symptoms may not be obvious or visible at the time of exposure. 

    • Having anonymous and/or multiple sex partners​ may increase your risk. 

    • Condoms cannot always prevent mpox since the rash can occur on different parts of the body. 

  • ​Do not share items with someone who has an unexplained rash. Avoid sharing items such as: 

    • ​Towels or bedding 

    • Sex toys or fetish gear 

    • Toothbrushes 

    • Dishware 

  • ​Wash your hands often with soap and water or an alcohol-based hand sanitizer (at least 60% alcohol). This is especially important after intimate contact. 

  • Be mindful of mpox symptoms. If you notice any new rashes or sore(s), avoid intimate contact until you can see a provider for testing. 

  • Follow international travel recommendations. This may mean getting the mpox vaccine if you are travelling to regions where clade I mpox has been spreading. 

Who is most affected by mpox? 

To date, most mpox infections in California have been among gay, bisexual, or other men who have sex with men and their social networks. Many infections have been associated with sexual or other intimate contact. Activities that may increase your risk of exposure to mpox include: ​

  • ​​Having more than one sex partner 

  • Group or anonymous sex like at bathhouses or sex clubs 

  • Having a sex partner who is at​ risk for mpox exposure

  • Traveling to a country where clade I mpox is spreading​ 

Also, there have been travel-related clade I mpox infections in the U.S. and California. These infections have been among international travelers who were exposed while traveling in a country where clade I mpox has been spreading. Travel exposure risks may include: 

  • ​​Intimate or sexual contact 

  • Getting a massage 

  • Visiting a home where someone is sick with mpox 

  • Products or meat from wild animals that naturally carry mpox​

Both types of mpox can cause more severe illness in people who have certain health conditions, such as HIV. ​

​I am sexually active. How can I protect myself and my partner(s)?

  • Not having sex or close contact if you or your partner(s) have mpox symptoms, such as a new or unexplained rash or sores or feels sick until they see a health care provider.  

  • ​Reducing the number of sexual or close contact partners, especially if their recent sexual history is unknown.  

  • Making a habit of exchanging contact info with any new partner for sexual health follow-up if needed.  

  • Limiting going to sex or circuit parties or spaces with intimate contact with multiple people.  

  • Using condoms and gloves during sexual activity:   

    • ​​Condoms (latex or polyurethane) may protect the mouth, penis, anus, or vagina from exposure to mpox; however, condoms alone may not prevent all exposures to mpox since the rash can occur on other parts of the body.  

    • Gloves (latex, polyurethane or nitrile) may reduce exposure if inserting fingers or hands into the anus or the vagina. The gloves must cover all exposed skin and be removed carefully to avoid touching the outer surface.  

    • Not sharing toothbrushes, towels, clothing, bedding, fetish gear, or sex toys.  

    • Washing hands and all gear, towels, bedding and sex toys thoroughly after use or sex act. 

What if I get mpox? 

I think I was exposed

  • ​Get the mpox vaccine before symptoms develop. If you think you have been exposed to mpox and you haven’t already received both vaccine doses, getting the vaccine ASAP (within 14 days) may still provide some protection. ​Find mpox vaccine near you. 

  • ​Watch for symptoms. ​​Be alert for any new symptoms, which can feel like a cold or flu before the rash starts. Sometimes, sores develop in hard-to-see places like inside the mouth or rectum (butt). 

  • ​​Consider avoiding close or intimate contact with others for 21 days after exposure. 

Testing and treatment ​

See your health care provide​r if you notice any rash or sores. Ask for mpox testing if you think you may have mpox. 

  • ​The test for mpox is a swab of the rash or sore. Most primary care or urgent care clinics can do this testing if requested. 

  • While uncommon, infections after vaccination are possible. And very rarely, people can get mpox more than once. These infections usually have more mild symptoms. 

Talk to your health care provider if you need help with your symptoms. 

  • ​Most mpox infections heal with self-care at home. Your provider may recommend medicines for your symptoms. ​

  • ​​It can take several weeks for the rash to fully heal. Good skin care can promote healing of the rash​ (PDF). Avoid touching the rash or sores. This can cause them to spread more around your body or get infected.​

  • ​Additional treatments may be needed for people who are very sick with mpox or who are at a higher risk for getting very sick. Talk with your provider. 

Prevent spreading mpox to others. 

  • ​Isolate from others and pets at home until the rash is healed. If you must be around others, make sure all parts of the rash are covered with clothing, gloves, or bandages. Wear a face mask. 

  • Clean and disinfect shared areas in the home. The virus can survive for a while on linens, clothing and surfaces like doorknobs and faucet handles. Disinfection is recommended for all areas where you spent time. ​

  • Notify close contacts who may have been exposed. ​​Your local health department can help with anonymous notifications. 

For more information, see What to Expect If You Are Diagnosed with Mpox. 

Resources for everyone 

  • ​Mpox Vaccination: Find Vaccine Near You 

  • How Mpox Spreads (CDC) 

  • How to Prevent Mpox (CDC) 

  • Signs and Symptoms of Mpox (CDC) 

  • ​If You’re a Close Contact to Mpox (CDC) ​

  • What to Do If You Are Sick (CDC) 

  • Preventing Mpox While Traveling (CDC) 

Resources for health care providers and public health 

  • ​​See CDPH Mpox Guidance​ for resources. ​​​​​​​​​​​​​​​​​​​​​​​​​

How Can We Help You?

Connect with CDPH for additional mpox resources.

Contact CDPH STD Control Branch Mpox Team

If you need further clarification or have questions, comments, and concerns regarding CDPH Mpox, submit an inquiry​.

Contact Your Local Public Health Department

Reach out to your local health department with any questions.​

Page Last Updated : October 18, 2025
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