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State of California—Health and Human Services Agency
California Department of Public Health

November 4, 2020

Medical Waste Generators, Medical Waste Transporters, Offsite transfer station and Treatment facilities, Local Enforcement Agencies, and Trauma Scene Waste Practitioners

Novel Coronavirus Disease 2019 (COVID-19) Medical Waste Management - Interim Guidelines

This Guidance is no longer in effect and is for historical purposes only.

COVID-19 Medical Waste Management

The California Department of Public Health (CDPH), Medical Waste Management Program (MWMP) regulates the generation, handling, storage, and treatment of medical waste by providing oversight under the authority of the Medical Waste Management Act (MWMA). This document provides general guidance for the management of Novel Coronavirus Disease 2019 (COVID-19) contaminated medical waste based on federal guidelines and standards.

As of the date of this publication, there are no additional regulatory handling, marking, storage, transportation or treatment requirements for medical waste contaminated with COVID-19.

Follow the requirements of the Medical Waste Management Act statutes for managing medical waste in California.  Follow the US Department of Transportation (USDOT) regulations for packaging, labeling and offsite transportation of Regulated Medical Waste (RMW). The details of RMW and Category B infectious substances transportation is discussed in USDOT Hazardous Materials Regulations (HMR) 49 Code of Federal Regulations 173.197.

General Guidance


The Centers for Disease Control and Prevention (CDC) has released general guidance on Coronavirus Disease 2019 (COVID-19) which should be reviewed closely and checked regularly. This includes appropriate infection prevention and control practices for the handling and packaging of items contaminated with COVID-19.


The CDPH webpage, Coronavirus Disease 2019, provides general information on how to limit the spread of COVID. Additionally, the CDPH Center for Healthcare Quality (CHCQ) released an All Facilities Letter, AFL 20-14 (PDF), on February 19, 2020, providing interim guidance for Environmental Infection Control for COVID-19.


Additional guidance can also be found on the Occupational Safety and Health Administration (OSHA) website, COVID-19 overview.

Who to Contact

Facilities may also contact their Local Enforcement Agency (LEA), County Health Director, and CDPH Medical Waste Management Program regarding COVID-19 waste management queries.

Personal Protection Equipment (PPE)
Clear guidelines for healthcare professionals protection are available at OSHA control and prevention. Additionally, the CDC advises that administrative rules and engineering controls, environmental hygiene, correct work practices, and appropriate use of PPE are all necessary to prevent infections.

Disinfecting Agents
Coronaviruses are enveloped viruses, meaning they are easily disinfected with the use of appropriate disinfectant products per the US Environmental Protection Agency (EPA). For cleaning and decontamination information, consult CDC guidance for cleaning and disinfecting environments, including those contaminated with other coronavirus.

Trauma Scene Waste Practitioners
Trauma scene waste practitioners who are registered with the MWMP should follow their disinfecting procedures as established. Wear appropriate PPE, follow the OSHA Bloodborne Pathogens standard, and use the technologies and chemicals appropriate to the task for cleanup and disinfection. Additionally, refer to Chapter 9.5 of the MWMA on the statutes for Trauma Scene Waste Management.

Packaging COVID-19 Contaminated Waste
Waste from COVID-19 patients is handled as standard RMW. Refer to the MWMA for the statutes in California. The CDC has provided general, not COVID-19 specific, recommendations in the Guidelines for Environmental Infection Control in Health-Care Facilities (2003). CDC guidance states that the management of RMW should be performed in accordance with routine procedures as it has not been implicated in the transmission of Severe Acute Respiratory Syndrome Coronaviruses (SARS-CoV) including COVID-19.

Transportation within a Facility and Offsite

Facility operation and logistics vary among health care facility types requiring each facility to develop a Medical Waste Management Plan (Plan) tailored to address the needs at each facility while maintaining compliance with the MWMA. Each Plan should include the procedures of transporting waste from the room it is generated in to the interim storage room and ultimately to the Designated Accumulation Area. From this area, the waste will then be treated onsite or prepped for transportation offsite for treatment.

All containers for offsite transport should be USDOT approved. Pharmaceutical waste shall also be transported in compliance with the United States Drug Enforcement Administration (DEA) requirements. RMW and Category B infectious substances are listed in the USDOT Hazardous Materials Regulations (HMR) 49 Code of Federal Regulations 173.197. As of the publication date of this document, there is no requirement for any additional specialized packaging or marking for this waste required per regulations.

A special permit issued by the USDOT is not required to transport RMW contaminated with COVID-19.

Treatment of COVID-19 Waste

RMWs are treated or decontaminated to reduce the microbial load in the waste and to render the by- products safe for further handling and disposal. Treatment processes are permitted under each state's medical waste statutes and regulations and treatment methods may include autoclaving, incineration, chemical disinfection, grinding/ shredding/disinfection methods, and energy-based technologies (e.g., microwave or radiowave treatments). Waste treated in California shall follow the requirements outlined in the MWMA Sections 118215 – 118245.

If onsite treatment is not available or the health care facility chooses to not treat the waste onsite, the facility should package the waste appropriately for transport offsite (see Transportation section above) to a permitted medical waste transfer station and/or treatment facility.

Waste shall be taken to a permitted Transfer Station and Offsite Treatment facility (TSOST) for treatment. A list of permitted TSOST facilities in California can be found on the Medical Waste Management Program website.

If the waste is being sent out of the State of California for treatment, check with the receiving State for their requirements on the treatment of medical waste and specifically medical waste contaminated with COVID-19.

Once the waste has been efficaciously treated by a permitted medical waste facility, the waste is no longer considered RMW and can be managed as solid waste. Treatment facilities shall coordinate with the solid waste landfill for final disposal of the waste. Direct efficacy questions for medical waste treatment to your Local Enforcement Agency and/or to the CDPH, Medical Waste Management Program.

Originally Published on November 4, 2020