In the U.S., the most common species causing vibriosis are V. parahaemolyticus, V. alginolyticus, and V. vulnificus.
V. parahaemolyticus infection generally presents as acute gastroenteritis with fever that usually occurs after an incubation period of 24 hours. Symptoms usually last 1–7 days and are often self-limited.
V. alginolyticus often causes soft tissue infections, including those involving the eye and ear.
V. vulnificus can cause primary sepsis or serious wound infections. It is the leading cause of shellfish-associated death in the U.S. Sepsis is often accompanied by distinctive bullous skin lesions filled with hemorrhagic fluid. Systemic disease is frequently fatal, especially in persons with chronic liver disease, immunodeficiency, iron storage issues, end-stage renal disease, or diabetes.