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microbial diseases laboratory

Test Order - Modified Carbapenem Inhibition Method

Pre-Approval Required:

None

Supplemental Information or Form:

MDLB Lab Form AST-R, Antimicrobial Susceptibility Testing, is required for submission of samples. Submitter’s identification is required. Submitting Facility is required.

Performed on Specimens From:

Human sources

Acceptable Sample/Specimen Type for Testing:

A pure isolate of Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Enterobacter species or Pseudomonas aeruginosa. The isolate must be resistant to at least one carbapenem, i.e., imipenem, ertapenem, doripenem, or meropenem. If an isolate is positive for a known carbapenemase gene by a molecular method, the mCIM will not be performed.

Minimum Volume Required:

None

Storage & Preservation of Sample/Specimen Prior to Shipping:

Store at ambient temperature.

Transport:

Ship cultures on nonselective nutrient or similar agar in tubes with leak-proof screw cap closures.

Sample/Specimen Labeling:

Two patient identifiers on the specimen container and on the test requisition are required.

Shipping Instructions, Including Specimen Handling Requirements:

Ship at ambient temperature.

Test Methodology:

Phenotypic testing

Turnaround Time:

6-14 days

Interferences & Limitations:

The results of the mCIM are for epidemiological purposes, and are not intended to guide or monitor treatment for carbapenem resistant bacterial infections.

Additional Information:

None

MDL Points of Contact:

robin.hogue@cdph.ca.gov or peng.zhang@cdph.ca.gov
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