MDL History
California State Hygienic Laboratory, the forerunner of the current MDL or
Microbial Diseases Laboratory, was established by legislative act on July 1,
1905. The laboratory came into existence amidst a major public health crisis -
the first plague epidemic of San Francisco. The primary laboratory at Berkeley
campus of the University of California soon expended into three branch
laboratories in Los Angeles, Fresno, and Sacramento. Testing of rabies and the
production of antiserum also commenced as early as 1908 in the Pasteur Division
of MDL. A Division of Epidemiology soon followed in 2011. The State Board of
Public Health decided in 1912 to limit the State Laboratoryās direct testing to
cities of less than 25,000 inhabitants, which lead to earlier branch
laboratories becoming local public health laboratories. This decision became an
act in 1927 and led to the vast expansion of the local public health
laboratories. The State Laboratory took upon reference testing in close
collaboration with the local laboratories, thus contributing to the foundation
of a strong public health infrastructure, which exists to this day in
California.
From its inception, the State
Hygienic Laboratory provided high quality reference testing for the control of
communicable diseases such as diphtheria, typhoid, gonorrhea, and tuberculosis.
Other major functions included production of antitoxins and antisera, sanitary
microbiology, outbreak investigations, research, and teaching. By 1945, the State
Laboratory was performing approximately 10% of the total 1,297,774 tests
reported by the California public health laboratories with major emphasis on
complex culture examinations, confirmatory tests, animal inoculations,
serological techniques, and food and water analyses. Although some technology
has evolved, the scope of reference testing at MDL has remained unchanged for
more than hundred years.
Currently, MDL is part of the
Division of Communicable Disease Control (DCDC), Center for Infectious Diseases (CID), and the California Department of Public Health (CDPH). It is located since 2003 on the Richmond
Campus of the CDPH. The laboratory has five sections: Bacterial Diseases,
Foodborne and Waterborne Diseases, High Risk Pathogens,
Immunodiagnostic, Mycotic and Parasitic Diseases, and Mycobacterial
Diseases. Beside reference testing, MDL conducts applied research and teaching
of public health microbiologists and post-doctoral fellows. The laboratory has
60 staff members, which include laboratory directors, public health
microbiologists, research scientists, technicians and fellows.