Request for Applications (RFA) 24-10715
Hepatitis B Demonstration Project Grants

California's 2024 Budget Act made funding available for the establishment of demonstration projects to allow for innovative, evidence-informed approaches to improve the health and well-being of the most vulnerable and underserved Californians living with or at risk for hepatitis B virus (HBV) infection. This funding builds on funding included in the 2022 Budget Act and 2023 Budget Act that allowed for the establishment of six Hepatitis B demonstration projects. With this additional funding, CDPH will be making $1,300,000 available for encumbrance or expenditure until December 31, 2027, for two demonstration projects ($650,000 each). 

The purpose of this Request for Applications (RFA) is to select organizations to conduct these demonstration projects, with funding awarded in the form of local assistance grants. The duration of the funding period will be up to 2.5 years from the date of award.  The projects are intended to demonstrate approaches to serve the most vulnerable and underserved people in California living with or at risk for HBV infection with respect to:

• Hepatitis B virus screening
• Hepatitis B vaccination
• Linkage to hepatitis B care and
• Retention in hepatitis B care

An evaluation component will allow for an understanding of lessons learned and dissemination of lessons learned to strengthen new and existing programs. 

The project is aligned with California's goal to decrease the incidence of acute hepatitis B infection and improve care for persons living with hepatitis B. It is also consistent with the Viral Hepatitis National Strategic Plan (PDF, 1.68MB), which calls for the elimination of viral hepatitis as a public health threat by 2030. 

Any entity in any California county shall be eligible and may apply to operate a demonstration project pursuant to this provision, provided that it demonstrates experience and expertise in providing culturally appropriate services to the most vulnerable and underserved people living with or at risk for HBV infection. As indicated by surveillance data, priority populations include but are not limited to Asian American and Pacific Islanders, Sub-Saharan African communities, and people who use drugs and/or who are receiving substance use-related services. 

To apply for this competitive funding, Access the Hepatitis B Demonstration Project RFA (PDF)​ and submit all required documents listed in the RFA. 

Attachments

Attachment 1—Application Certification Checklist (Word)

Attachment 2—Application Cover Sheet (PDF)

Attachment 3—Project Synopsis (Word)

Attachment 4—Budget Justification (Word)

Attachment 5—Application Narrative (Word)

Please note the following important dates:

• RFA Released on 4/1/2025
• Deadline for submitting written questions to HepBDemoProjects@cdph.ca.gov by 4/15/2025, 5:00 P.M. PT
• Application submission deadline is 4/29/2025, 5:00 P.M. PT
• Notice of Intent to Award released on 5/27/2025

If you have any questions about the information on this page, please send an e-mail to HepBDemoProjects@cdph.ca.gov

Hepatitis B Demonstration Project Grants: Current Awardees

The California Department of Public Health Immunization Branch (CDPH/IZB) has awarded funding for Hepatitis B Demonstration Projects to the entities listed below. This funding was made available in California's 2022 and 2023 Budget Acts. The RFA process was highly competitive and CDPH/IZB wishes to thank all applicants for their thoughtful proposals and commitment to this work.

Current awardees are listed below in alphabetical order: ​