What you need to know
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Syphilis is a serious infection you can get if you have sex with someone who is infected.
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Protect yourself by using condoms every time you have sex and get tested regularly.
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Syphilis can affect many parts of your body. It increases your chances of getting HIV. It can be passed to your child during pregnancy or birth.
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Syphilis is curable with antibiotics. You could get infected again.
Syphilis basics
What is syphilis and how do you get it?
Syphilis is a curable, bacterial sexually transmitted infection (STI). A syphilis infection may increase one's risk of becoming infected with HIV. Syphilis can cause serious health complications even years after becoming infected.
Anyone who is sexually active can get syphilis through vaginal, anal, or oral sex without a condom. You get syphilis by direct contact with a syphilis sore (called a chancre) during sex. Most commonly the sores are at sites of sexual contact. Syphilis can also spread from an infected pregnant person to their unborn baby.
You cannot get syphilis through casual contact with objects, such as:
What are the symptoms of syphilis?
There are four stages of syphilis: primary, secondary, latent, and tertiary. Each stage has different signs, symptoms, and treatments. At any stage, syphilis can infect the brain and nervous system, the eye, or the ear. Treatment will stop your infection from moving to the next stage. It will also prevent passing it to someone else.
Primary Stage
At this stage one or many sores will appear where syphilis enters the body. A sore is called a chancre. These sores can occur anywhere, but are usually found around the:
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Penis
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Vagina or front hole
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Anus or back hole
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Rectum
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Lips or in the mouth
Sores are usually firm, round, and painless. The sores may not be noticed. They usually last 3‑6 to six weeks and will heal on their own. Even after the sores go away, syphilis is not cured. Treatment is still needed to stop the infection from moving to the next stage.
Secondary Stage
This stage usually starts with a rash. The rash can show up when your primary sores are healing or several weeks after the sores have healed.
The rash:
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Usually won't itch
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May be so faint that it isn't noticed
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Found on the palms of your hands and/or the bottoms of your feet
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Looks dry or rough
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Looks red to reddish-brown
Other symptoms may include:
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Mouth sores
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Wart-like growths around the vagina, penis, or anus
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Fever
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Swollen lymph glands
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Sore throat
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Patchy hair loss
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Headaches
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Weight loss
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Muscle aches
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Fatigue (feeling very tired)
The symptoms from this stage will go away on their own. But syphilis is not cured. Treatment is needed to stop the infection from moving to the next stage.
Latent Stage
There are no visible signs or symptoms of infection. Without treatment, syphilis will remain in your body. Although you will not have symptoms during this stage, syphilis can still cause complications.
Tertiary Stage
Most people with untreated syphilis do not develop tertiary syphilis. However, when it does happen, it occurs 10 to 30 years after the infection began. Tertiary syphilis is very serious and can result in death. It may damage many different organ systems including:
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Nerves
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Brain
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Blood vessels
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Heart
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Skin
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Bones
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Liver
Neurosyphilis, ocular syphilis, and otosyphilis
Without treatment, syphilis can spread to the brain and nervous system, the eye, or the ear. This can happen during any of the stages.
How do I avoid getting syphilis?
If you are sexually active, do the following to lower your chances of getting syphilis:
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Have an honest and open conversation with your health care provider. Ask them if you should get tested for syphilis or other STIs.
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Have sex only with partner(s) who have been tested and who do not have syphilis.
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Use condoms every time you have sex.
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If you think you were exposed to a syphilis sore or someone who has tested positive, tell your health care provider.
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You may need treatment to prevent developing syphilis yourself.
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Ask about doxy PEP (Doxycycline Post-Exposure Prophylaxis).
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Doxy PEP is medicine you take within 72 hours after having sex. It reduces your risk of infection from syphilis, chlamydia, and gonorrhea.
Get Tested
Testing is the only way to know if you are infected. Regular testing is the best way to identify infection early. Most of the time, health care providers will use a blood test to test for syphilis. Some will diagnose syphilis by testing fluid from a syphilis sore.
Early treatment can prevent complications from syphilis. Speak with a health care provider to determine how often you should get tested.
Who is most affected by syphilis?
Any sexually active person can get syphilis if they are exposed. Ask your health care provider if you should get tested for syphilis or other STIs.
Some people may be more likely to be exposed to syphilis. It is recommended they get regular testing.
You should get tested more frequently for syphilis if:
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You are a gay or bisexual cisgender man.
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You are a transgender or gender diverse person.
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You have HIV.
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You are taking pre-exposure prophylaxis (PrEP) for HIV prevention.
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You are taking doxy PEP.
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Your partner(s) have tested positive for syphilis or other STIs.
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You are pregnant.
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All pregnant people should receive syphilis testing three times during pregnancy.
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The first test should be as early as possible during the first trimester.
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The second test should be during the third trimester, around week 28 of pregnancy.
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The third test should be at delivery.
What if I get syphilis?
Treatment
Syphilis is curable with the right antibiotics from your health care provider. However, treatment might not undo any damage caused by the infection. It is important to get treatment as soon as possible. Having syphilis once does not protect you from getting it again.
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