Respiratory viruses

COVID-19 Vaccine Timing 2025-26

Routine Schedule

Age:	Vaccine:	If unvaccinated:	If had any prior doses, give 2025-26 doses:
6-23 months	Moderna – Spikevax (pediatric)	2 doses, 4-8 weeks apart	If 1 prior Moderna dose: wait 4-8 weeks before one dose. If 1 prior Pfizer dose: wait 4-8 weeks before 2 doses at least 8 weeks apart. If 2 or more prior Moderna or Pfizer doses: wait at least 8 weeks before one dose.
2-4 years^^	Moderna – Spikevax (pediatric)	1 dose	If 1 or more prior Moderna or Pfizer doses: wait at least 8 weeks before one dose.
5-11 years^^	Moderna – Spikevax (pediatric) or Pfizer–Comirnaty (pediatric)	1 dose	If 1 or more prior doses of any of the brands, then^: wait at least 2 months before one dose of either Spikevax or Comirnaty.
12+ years^^	Pfizer–Comirnaty (adol/adult) or Moderna–Spikevax (adol/adult) or Moderna–Mnexspike or Novavax–Nuvaxovid	1 dose. For people 65 years and older: wait 6 months^§ for an Additional Dose of any of the brands.	If 1 or more prior doses (of any of the brands), then^: Ages 12-64 years^^: wait at least 2 months^§before 1 dose of any of the brands. Ages 65+ years: wait at least 2 months^§ before 2 doses 6 months^§ apart of any of the brands.

^ Janssen (J & J) vaccine has been deauthorized. Follow schedule for 12+ years for any prior doses.

§ Minimum interval 2 months, except for Mnexspike, the minimum interval is 3 months.

^^ Vaccination is especially recommended to 2-64 year olds who have risk factors (PDF), are in close contact with others with risk factors, or have never been vaccinated.

View additional CDPH recommendations, pediatric vaccination guidance (PDF), and adult vaccination guidance. For storage and administration information, see COVID-19 Vaccine Product Guide (PDF).

COVID-19 Vaccine Timing 2025-26

If Moderately/Severely Immunocompromised

Age	Vaccine:	If unvaccinated:	If had any prior doses, give 2025-26 doses:
6 months – 4 years	Moderna – Spikevax (pediatric)	1^st dose, wait 4 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)*	If prior doses of Moderna or Pfizer at 6m-4y: 1 prior dose: wait 4 weeks before 2 doses at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose. 3 or more prior doses*: wait at least 8 weeks before 1 dose (for ages 5+ yrs, Pfizer dose is also OK). Additional Dose(s): wait 6 months^§.
5 – 11 years	Moderna – Spikevax (pediatric)	1^st dose, wait 4 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)* of Spikevax or Comirnaty	If prior doses of Moderna or Pfizer at 6m-4y: 1 prior dose: wait 4 weeks before 2 doses at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose. 3 or more prior doses*: wait at least 8 weeks before 1 dose (for ages 5+ yrs, Pfizer dose is also OK). Additional Dose(s): wait 6 months^§.
5 – 11 years	Pfizer–Comirnaty (pediatric)	1^st dose, wait 3 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)* of Spikevax or Comirnaty	1 prior dose: wait 3 weeks before 2 doses (Pfizer pediatric or adol/adult) at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose (Pfizer pediatric or adol/adult). 3 or more prior doses*: wait at least 8 weeks before 1 dose (Spikevax/Comirnaty). Additional Dose(s) of Spikevax/Comirnaty: wait 6 months^§.
12+ years	Pfizer–Comirnaty (adol/adult)	1^st dose, wait 3 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)* of any of the brands.	1 prior dose: wait 3 weeks before 2 doses (Pfizer pediatric or adol/adult) at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose (Pfizer pediatric or adol/adult). 3 or more prior doses*: wait at least 8 weeks before 1 dose (Spikevax/Comirnaty). Additional Dose(s) of any of the brands: wait 6 months^§.
12+ years	Moderna–Spikevax (adol/adult)	1^st dose, wait 4 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)* of any of the brands.	1 prior dose: wait 4 weeks before 2 doses (Spikevax or Mnexspike) at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose (Spikevax or Mnexspike). 3 or more prior doses*: wait at least 8 weeks before 1 dose (any brand). Additional Dose(s) of any of the brands: wait 6 months^§.
12+ years	Moderna–Mnexspike	1^st dose, wait 4 weeks for 2^nd dose, wait at least 4 weeks for 3^rd dose, wait 6 months^§ for Additional Dose(s)* of any of the brands.	1 prior dose: wait 4 weeks before 2 doses (Spikevax or Mnexspike) at least 4 weeks apart. 2 prior doses: wait at least 4 weeks before 1 dose (Spikevax or Mnexspike). 3 or more prior doses*: wait at least 8 weeks before 1 dose (any brand). Additional Dose(s) of any of the brands: wait 6 months^§.
12+ years	Sanofi/Novavax–Nuvaxovid	1^st dose, wait 3 weeks for 2^nd dose, wait 6 months^§ for Additional Dose(s)* of any of the brands.	1 prior dose: wait at least 3 weeks before 1 dose. 2 or more prior doses*: wait at least 8 weeks before 1 dose of any of the brands. Additional Dose(s) of any of the brands: wait 6 months^§.