For Clinicians - Collection Information
Over 99% of the babies born in California are screened. The actual sample of newborn blood is obtained by the second day of life by a heel-stick. State regulations require that the sample be collected between 12 and 48 hours of life, prior to a red blood cell transfusion. If for any reason the newborn screen is collected prior to 12 hours (e.g., transfusion, discharge earlier than 12 hours), a second screen will be required.