Welcome to the State of California 

The activities of the California Prenatal Screening Program (PNS) are focused on detecting birth defects during pregnancy. PNS is working to assure prenatal screening services and follow-up diagnostic services, where indicated, are available to all pregnant women in California.  Prenatal screening currently offers three types of screening tests to pregnant women in order to identify individuals who are at increased risk for carrying a fetus with a specific birth defect.

Sequential Integrated Screening - Combines first and second blood test results with Nuchal Translucency (NT) ultrasound results. This type of ultrasound is done by clinicians with special training. It measures the back of the fetus' neck. This measurement helps screen Down syndrome (trisomy 21). (Note: the Screening  Program does not pay for NT ultrasounds).

Serum Integrated Screening - Combines a first trimester blood test screening result (10 weeks-13 weeks 6 days) with a second trimester blood test screening result (15 weeks-20 weeks).

Quad Marker Screening - One blood specimen drawn at 15 weeks - 20 weeks of pregnancy (second trimester test).

The Prenatal Screening Program provides pregnant women with a risk assessment for open neural tube defects (NTD), Down syndrome (trisomy 21), trisomy 18 and SLOS (Smith-Lemli-Opitz Syndrome) through one or two blood tests. The screening test indicates risk, but does not diagnose fetal birth defects.

For women with screening results indicating a high risk for a birth defect, the Program provides free follow-up diagnostic services at State-approved Prenatal Diagnosis Centers (PDCs) (PDF). Services offered at these Centers include genetic counseling, ultrasound, and amniocentesis. Participation in the screening testing and follow-up services is voluntary. The cost of the testing through the Prenatal Screening Program is $221.60.

 Please leave comments and questions at pns@cdph.ca.gov

Prenatal Screening Program Patient Booklets and Consents
Screen Positive Information for Patients: English, Español, 中文, 韓語, 越南語
News, Hot Topics & Information
Health Information
Courier Information for Labs and Draw Stations
Email Prenatal Screening at: pns@cdph.ca.gov
Last modified on: 4/24/2017 4:13 PM