Welcome to the State of California 

MDL logo

Test Order

Streptococcus pneumoniae Real-Time PCR

Pre-Approval Required


Supplemental Information or Form

1.    A sterile body site specimen that has not yielded growth on bacterial culture but is from a patient with a high clinical suspicion of bacterial meningitis or sepsis.

2.    A completed submittal form with 2 patient identifiers (e.g. name and date of birth). Please include the date of collection and information on the patient’s suspected disease, clinical findings, antibiotics administered, and culture results.

3.    For a CSF specimen please indicate its WBC count, protein and glucose levels

4.  VPP-Form01.Bacterial Meningitis Test Request

Performed on Specimens from


Acceptable Sample/Specimen Type for Testing

1.    Minimum 0.5 ml blood, preferably preserved in EDTA

2.    Minimum 0.5 ml cerebrospinal spinal fluid

Minimum Volume Required


Storage & Preservation of Specimen Prior to Shipping


Transport Medium


Specimen Labeling


Shipping Instructions which Include Specimen Handling Requirements

Ship at 4°C on a cold pack using appropriate DOT/IATA approved shipping procedures.

Test Methodology

Real-time PCR

Turnaround Time

1-5 days

Interferences & Limitations

Culture positive specimens or those collected from nonsterile body sites are not appropriate for this testing

Additional Information

Please contact the MDL Vaccine Preventable Pathogens Unit for special consideration if any of the above criteria cannot be met.

MDL Points of Contact

Vaccine Preventable Pathogens Unit (510) 412-3700

Monday-Friday 8 AM to 5 PM PT

Emails: jennifer.kyle@cdph.ca.gov or fengfeng.xu@cdph.ca.gov

Last modified on: 8/26/2015 4:05 PM