Welcome to the State of California 

MDl logo

Test Order

Mycobacterium tuberculosis Complex:
Drug Susceptibility Testing, First Line

Pre-Approval Required

None

Supplemental Information or Form

Form LAB 444 (03/12) (MDL-N-25), EXAMINATION FOR MYCOBACTERIUM TUBERCULOSIS DRUG SUSCEPTIBILITY

Performed on Specimens from

California local public health laboratories

Acceptable Sample/Specimen Type for Testing

Pure culture

Minimum Volume Required

None

Storage & Preservation of Specimen Prior to Shipping

Incubated at 35-37°C (or refrigerated).

Transport Medium

None

Specimen Labeling

Patient’s name, accession number, inoculation date or subculture date.

Shipping Instructions which Include Specimen Handling Requirements

Ship as infectious substance.

Test Methodology

By MGIT 960. Drugs routinely tested are isoniazid (INH) 0.1 μg/ml, rifampin 1 µg/ml, ethambutol 5 µg/ml, and pyrazinamide 100 µg/ml.  When there is resistance to rifampin, or to any two first line drugs, second line drug susceptibility testing is performed.  When there is resistance to INH at a concentration of 0.1 μg/ml, testing at  0.4 μg/ml is performed.

Turnaround Time

7 to 14 days

Interferences & Limitations

Results unattainable because culture submitted is mixed with nother mycobacteria (usually Mycobacterium avium complex) or mixed with a non-mycobacteria contaminant.

Additional Information

None

Mycrobacteriology (drug susceptibilities) contact

(510) 412-3929

 
 
Last modified on: 9/3/2013 3:58 PM