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The California Antimicrobial Stewardship Program Initiative


The CDPH HAI Program supports the Antimicrobial Stewardship Program Initiative to provide consultation and education for assisting California hospitals and other healthcare facilities to implement these important local programs, necessary for strengthening the optimization of antimicrobial utilization. The purpose of an antimicrobial stewardship program in a healthcare facility is to measure and promote the appropriate use of antimicrobials by selecting the appropriate agent, dose, duration, and route of administration, to improve patient outcomes while minimizing toxicity and the emergence of antimicrobial resistance. Antimicrobial stewardship is essential in the control of Clostridium difficile infections and the emergence of infections due to mutidrug resistant organisms.

California law requires that general acute care hospitals implement programs for monitoring the judicious use of antibiotics and requires a quality improvement committee with responsibility for oversight. California is the only state with this type of mandate. CDPH performed a statewide assessment of antimicrobial stewardship programs and published the findings in 2013 at The State of Antimicrobial Stewardship in California

We are pleased to launch our new Spotlight on Antimicrobial Stewardship Programs project, which allows hospitals to share their antimicrobial stewardship program strategies and progress, and identifies California physician, pharmacists, and infection prevention leaders willing to serve as mentors to other hospitals in various stages of antimicrobial stewardship program implementation. This webpage will update each hospital's implementation progress as more antimicrobial stewardship activities are fully realized over the coming months and years. Additional volunteer hospitals will be added to the site on a quarterly basis.


Current program activities include:

  1. Spotlight on Antimicrobial Stewardship Programs (ASP) Project helps define antimicrobial stewardship programs and activities, and spotlights volunteer hospitals that want to highlight and share with others their program progress. Please refer to the Spotlight on ASP Invitation for further details regarding participation.
  2. Use of a statewide assessment of antimicrobial stewardship programs to develop evidence-based recommendations on how to implement or strengthen antimicrobial stewardship programs given available resources and facility attributes..
  3. Consultative advice and practical evidence to facilities in order to gain administrative, pharmacy and provider buy-in.
  4. Developing recommendations with the Antimicrobial Stewardship Subcommittee of the California HAI Advisory Committee.
  5. Defining activities that comprise antimicrobial stewardship programs in California hospitals.


  1. Dellit, TH et al. Infectious Disease Society of American and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship. Clin Infect Dis 2007;44:159-77.
  2. http://www.hhs.gov/ash/initiatives/hai/9-hai-plan-outreach.pdf
  3. Department of Health and Human Services, Center for Medicare and Medicaid Services. “Interpretive Guidelines for Long-Term Care Facilities, Tag F441”, CMS Manual System Pub. 100-07 State Operations Provider Certification, Transmittal 51, July 30, 2009.
  4. http://www.dhcs.ca.gov/provgovpart/initiatives/nqi/Documents/SB739.pdf
  5. Policy Statement on Antimicrobial Stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS) Infection Control and Hospital Epidemiology, Vol. 33, No. 4, Special Topic Issue: Antimicrobial Stewardship (April 2012), pp. 322-327 - - see recommendations
  6. Antimicrobial Stewardship: A Collaborative Partnership between Infection Preventionists and Health Care Epidemiologists. Julia Moody, Sara E. Cosgrove, Russell Olmsted, Edward Septimus, Kathy Aureden, Shannon Oriola, Gita Wasan Patel and Kavita K. Trivedi. Infection Control and Hospital Epidemiology , Vol. 33, No. 4, Special Topic Issue: Antimicrobial Stewardship (April 2012), pp. 328-330 - - see recommendations
  7. The State of Antimicrobial Stewardship in California

For additional information or comments, please contact: cdphhaiprogram@cdph.ca.gov


Last modified on: 4/30/2014 2:24 PM