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 The California Antimicrobial Stewardship Program Initiative

The use of antibiotics is the most important factor in the development of antimicrobial resistance. Antimicrobial stewardship programs aim to promote and measure use of the appropriate agent, dose, duration, and route of administration of antimicrobial agents, in order to improve patient outcomes while minimizing adverse events including toxicity, Clostridium difficile infections and the emergence of antimicrobial resistant organisms. Antimicrobial stewardship programs improve the quality of patient care and patient safety, and can also reduce excessive costs attributable to inappropriate antimicrobial use.

California is the first and remains the only state to enact antimicrobial stewardship legislation. Since 2008 California law required that general acute care hospitals develop a process for monitoring the judicious use of antibiotics and that the results are monitored by quality improvement committee(s). In September 2014, California Senate Bill 1311 was signed into law, further requiring hospitals to adopt and implement an antimicrobial stewardship policy in accordance with guidelines established by federal government and professional organizations, and to establish a physician-supervised multidisciplinary antimicrobial stewardship committee with at least one physician or pharmacist who has undergone specific training related to stewardship. Nationally, a presidential Executive Order - Combatting Antibiotic-Resistant Bacteria, also issued in September 2014, requires federal agencies to review existing regulations and propose new regulations or other actions to require hospitals to implement robust stewardship programs that adhere to best practices; agencies will also be required to define, promulgate and implement stewardship programs in other settings such as long-term care facilities and outpatient settings.

The CDPH HAI Program California Antimicrobial Stewardship Program Initiative provides guidance and support for California hospitals and other healthcare facilities to implement these important local programs.

California Antimicrobial Stewardship Program Initiative activities:

List of Spotlight Hospitals Image 

Antimicrobial Stewardship Resources:

Society for Healthcare Epidemiology of America (SHEA) / Infectious Disease Association of California (IDAC) Antimicrobial Stewardship Conference: http://www.shea-online.org/Education/2015AntimicrobialStewardshipConference.aspx

American Hospital Association toolkit: http://www.ahaphysicianforum.org/resources/appropriate-use/antimicrobial/index.shtml

CDC's Core Elements for Hospital Antibiotic Stewardship Programs and Checklist for Hospital Antibiotic Stewardship Programs.

Infectious Diseases Society of America (IDSA): http://www.idsociety.org/Antimicrobial_Agents/#Antimicrobial Stewardship

SHEA: http://www.shea-online.org/PriorityTopics/AntimicrobialStewardship.aspx

Stanford School of Medicine: http://bugsanddrugs.stanford.edu/

Greater New York Hospital Association http://www.gnyha.org/whatwedo/quality-patient-safety/infection-control-prevention/

Antimicrobial Stewardship References:


Department of Health and Human Services, Center for Medicare and Medicaid Services. "Interpretive Guidelines for Long-Term Care Facilities, Tag F441", CMS Manual System Pub. 100-07 State Operations Provider Certification, Transmittal 51, July 30, 2009.

Policy Statement on Antimicrobial Stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS) Infection Control and Hospital Epidemiology, Vol. 33, No. 4, Special Topic Issue: Antimicrobial Stewardship (April 2012), pp. 322-327 -- see recommendations

Antimicrobial Stewardship: A Collaborative Partnership between Infection Preventionists and Health Care Epidemiologists. Julia Moody, Sara E. Cosgrove, Russell Olmsted, Edward Septimus, Kathy Aureden, Shannon Oriola, Gita Wasan Patel, and Kavita K. Trivedi. Infection Control and Hospital Epidemiology, Vol. 33, No.4, Special Topic Issue: Antimicrobial Stewardship (April 2012), pp. 328-330 -- see recommendations

Last modified on: 8/11/2015 3:10 PM